Best Kratom for Anxiety and Depression: Top Strains Reviews

Both anxiety and depression affect millions of people globally. The World Health Organization recently reported approximately 300 million people around the world suffer from anxiety in particular. Similarly, depression affects a staggering number of people, with the figures being similar to those for anxiety.

There are ways to treat these mental health conditions. Many people turn to therapy, and some take the route of medication. However, others may need something else to bring them back to their usual, energetic, and calm selves.

For those who haven’t had much luck with other therapies or prefer a more natural approach to healing depression and anxiety, kratom is an option.

We’ve gathered everything you need to know about how kratom works for these conditions, so you can find the strains that target your symptoms. Keep reading our guide to learn more!

Best Kratom Strains for Anxiety & Depression

Kratom is a plant originally from Southeast Asia with a history of easing anxiety, depression, chronic pain, energy, and focus. Depending on the chosen strain and dosage taken, you can achieve several effects from kratom.

So, what is the best kratom for anxiety & depression? Every person will react differently, but we’ve researched the most popular strains and narrowed them down to the top three.

Maeng Da Kratom

The Maeng Da strain is native to the countries of Malaysia, Indonesia, and Thailand. You can find Maeng Da in all three major strains: white, red, and green. Regardless of the strain you choose, all Maeng Da strains rate highly as some of the best kratom for anxiety & depression.

The Maeng Da strains deliver consistent effects, durability, and high quality, but each still offers unique effects.

Red Maeng Da kratom is one of the most popularly searched terms, making it incredibly common and beloved by many. This particular strain is extremely high in the alkaloid 7-hydroxymitragynine, critical for the anti-anxiety and sedating effects. Those who struggle with anxiety, especially while trying to fall asleep at night, will love this strain.

Green Maeng Da, on the other hand, is incredibly potent. This is some of the best kratom for anxiety & depression that blends both red and white strains. You’ll find this strain to be more of a stimulant than a sedative, so it may be beneficial for those having trouble getting up in the morning or making it through the responsibilities of the day.

Maeng Da makes an excellent anti-depressant and anti-anxiety supplement because it balances neurotransmitters in the brain. It increases serotonin production, which is the ‘happy hormone.’ Your new and improved serotonin levels can help fight against anxiety and depression.

Certain chemical compounds in the Maeng Da strains also interact with the brain’s opioid receptors. They help mitigate brain fatigue and lift some burden of what may feel like heavy mental tasks. For people with depression, this improved energy and mood enhancement will be life-changing.

You can increase your concentration and focus with more excellent mental stability after taking an appropriate dose of Maeng Da.

Overall, Maeng Da is some of the best kratom for anxiety & depression because it can also relieve pain, helping you find a reason to get up and think more positively.

Benefits of Maeng Da Kratom

  • Balances neurotransmitters and increases serotonin production (the ‘happy hormone’)
  • Boosts mental strength
  • Improved mental stability
  • Pain relief alleviates anxiety or depression due to chronic pain

Green Malay Kratom

Green Malay is a strain that comes straight from Malaysia, though it’s possible to find it in other regions. This strain has a distinctively dark color, making it easy to pick apart from the rest.

Green Malay gears more toward depression and social anxiety than it does for generalized anxiety. The reason is that it’s more on the stimulant side.

Most users take it first thing in the morning. It boosts energy, improves concentration, and sharpens focus to get things done.

If you want to feel more sedating effects, you can take Green Malay in a higher dose just before bed.

According to Compare Kratom, Green Malay is some of the best kratom for anxiety & depression because it reduces stress quickly and returns to a healthy level of nerves. You’ll notice the calming effects, especially when taking it at higher doses.

Rather than provide jitters, Green Malay delivers smooth, balanced energy. It will help you get through the day feeling energized and at peace.

If you’re feeling weak due to your anxiety or depression, you’ll love the performance you get from just one dose of Green Malay. It can help with digestion, boost your immune system, and even increase your appetite. For people who struggle to eat and care for themselves during mental health episodes, this can be a beacon of hope.

Sometimes, the first step to feeling better is pain management. Once that is under control from the analgesic effects of Green Malay, you can focus on your mental health and motivation.

Benefits of Green Malay Kratom

  • Stress relief
  • Balanced energy (no jitters exacerbating anxiety symptoms)
  • Increased motivation and performance
  • Pain management

Red Bali Kratom

Red Bali Kratom is some of the best kratom for anxiety & depression mainly because of its strength and effects directly related to these two conditions.

A strain coming from Indonesia, Red Bali is one of the top-selling types in the United States. Red Bali is available at a reasonable price and is always highly potent, meaning you don’t have to take quite as much to get the desired effects.

Red Bali has a lot of the alkaloid 7-hydroxy mitragynine, also found in Maeng Da. When you take small doses of Red Bali, it’s great for a mild energy boost or afternoon pick-me-up. It can also enhance mood and energy, making it an excellent choice for depression or social anxiety.

Red Bali is not one of the fastest working strains on the market, but it has potent effects if you’re patient. Red Bali is especially beneficial for pain and inflammation in the body. You will likely build up a tolerance to the strain over time, leading to gradually higher doses.

Red Bali can also have powerfully sedating effects, making it especially beneficial for those with anxiety attacks or people that need help falling asleep at night. If you struggle with anxiety-fueled insomnia, the powerfully sedating effects of Red Bali kratom can do the job for you.

Note that there’s the risk of taking too much and feeling the sedative effects. Therefore, experts don’t recommend taking this particular strain first thing in the morning. It’s better for the afternoons, evenings, or just before bed.

Responsible for all types of anxiety, depression, and pain relief, it’s no wonder that Red Bali has the highest Google search volume of the best kratom for anxiety & depression.

Benefits of Red Bali Kratom

  • Sedative to manage anxiety-fueled insomnia
  • Energy boost
  • Mood enhancement
  • Potent analgesic for dealing with anxiety/depression due to chronic pain

How Does Kratom Work for Anxiety?


The best kratom for anxiety & depression is one that works for you, regardless of the color or strain. That said, it’s helpful to understand more about how kratom works for anxiety so you can pick a strain that will have the most profound effects on you personally.

Kratom works very similarly to opioids, like morphine or codeine, but on a milder level. However, kratom is not an opioid. It is also nowhere near as addictive as morphine or codeine, making it an excellent option for someone trying to wean off opioid use.

Instead, kratom relieves anxiety and depression via the various alkaloids it contains. These alkaloids interact with the brain’s neurotransmitters, releasing serotonin and other chemical compounds in the brain that affect mood.

Kratom can help you from the minute you wake up to just before falling asleep. In the morning, a small dose can boost your mood and sharpen your mental focus. It works even when your depression is telling you that you can’t get out of bed.

According to, it’s a helpful pick-me-up to get through the day to uplift mood and enhance physical performance in the afternoon. If you struggle with pain that flares up in the daytime, it can also provide analgesic effects to reduce the severity of that pain. For those whose anxiety or depression is a result of chronic pain, kratom is a lifesaver.

At night, taking a larger dose of kratom can produce powerful sedating effects. It can help you fall asleep faster, thus creating a regular and healthy sleeping pattern. Those who struggle with anxiety can break harmful habits and promote much healthier ones.

Where to Buy the Best Kratom for Anxiety?

There are a few different strains that you should try if you want to soothe your anxiety or depression. Before you find the first kratom retailer in your neighborhood or go online to order the cheapest and fastest product, read the section below.

We’ve put in hours of research to find the best kratom sellers for anxiety and depression, so you don’t have to. Here are three sellers that offer quality and safe kratom.

Kona Kratom

Kona Kratom is an excellent place to try when you’re first starting. The company has a vast selection of strains, from popular strains like Borneo and Malay to more niche offerings like Maeng Da.

The company also has something that other vendors don’t: a long-lasting relationship with its farmers in Southeast Asia. The company works closely with its growers, which means they can also offer better prices and consistent quality. It passes these benefits onto the customers.

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Key Points

  • Huge selection
  • Great prices
  • An approved vendor with the American Kratom Association
  • Third-party testing on all strains
  • A solid relationship with SE Asian kratom farmers

Star Kratom

If you’re strict on certification and finding a vendor that can get you the best kratom for anxiety & depression fast, look no further than Star Kratom. Star Kratom is an American Kratom Association-approved vendor with speedy shipping. Their orders arrive 2-3 days sooner on average than other vendors.

While a relatively new vendor, its speedy delivery system and superb customer service have made it incredibly popular in a short period. The Star team proved invaluable during the pandemic when other vendors struggled to keep up with home deliveries. Enjoy the money-back guarantee and fast shipping when you choose Star!

Key Points

  • Speedy shipping
  • Great selection
  • A small, family-owned business
  • An approved vendor with the American Kratom Association
  • Third-party testing on all strains
  • Money-back guarantee, no questions asked

VIP Kratom

VIP Kratom has strict vetting procedures before letting any strain on their site. Its commitment to quality means that when you’re seeking the best kratom for anxiety & depression, you’ll find only premium, grade-A strains with VIP Kratom.

The company is so committed to quality that it even offers fewer strains. Only top-notch strains that go through third-party testing will make it onto the VIP Kratom website. If you want to get what you pay for, this vendor is your best bet.

Key Points

  • Top-shelf kratom
  • Rare and exotic strains not found elsewhere
  • Potent strains
  • An approved vendor with the American Kratom Association
  • Third-party testing on all strains

Conclusion — Using Kratom for Anxiety and Depression

Kratom is a natural way of dealing with anxiety and depression that doesn’t involve medications or therapy. With the right dosage during the day or at night, you can ease anxious thoughts, uplift mood, and enhance your energy with no adverse side effects.

Just be sure to purchase your products from one of the most trusted retailers above and look for Maeng Da, Red Bali, and Green Malay kratom. These are the best kratom for anxiety & depression because their alkaloids reduce stress, anxiety, and pain.

While Maeng Da is great if you want a robust strain with high alkaloid content, Green Malay works better for mood enhancement and a boost in productivity without any jitters associated with stimulants. Red Bali is the best kratom for anxiety & depression if you want a potent sedative to help with insomnia and chronic pain.

If you’re ready to purchase, consider reaching out to the vendors listed above and experience for yourself the best kratom for anxiety and depression.

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